FRL-1, a member of the EGF-CFC family, is essential for neural differentiation in Xenopus early development
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چکیده
منابع مشابه
FRL-1, a member of the EGF-CFC family, is essential for neural differentiation in Xenopus early development.
Recent studies indicate an essential role for the EGF-CFC family in vertebrate development, particularly in the regulation of nodal signaling. Biochemical evidence suggests that EGF-CFC genes can also activate certain cellular responses independently of nodal signaling. Here, we show that FRL-1, a Xenopus EGF-CFC gene, suppresses BMP signaling to regulate an early step in neural induction. Over...
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ژورنال
عنوان ژورنال: Development
سال: 2003
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.00430